منابع مشابه
Human eosinophil-lymphocyte interactions.
While the eosinophil's effector functions clearly can contribute to the pathogenesis of allergic diseases, the evolutionary benefit to having eosinophils as a distinct class of leukocyte is not clear, especially if one must reconsider the nominally beneficial role of eosinophils in parasite host defense, Eosinophils are equipped to respond to lymphocytes and their cytokines (and not solely the ...
متن کاملLymphocyte-fibroblast interactions.
Chronic inflammatory reactions are usually characterized by inflammatory cell accumulation in the extravascular connective tissue. In such sites, inappropriate activation of circulating or resident lymphocytes becomes self-perpetuating and can lead to chronic tissue destruction. In addition to that, the locally infiltrated lymphocytes should have an opportunity to interact directly with fibrobl...
متن کاملHuman eosinophil-airway smooth muscle cell interactions.
Eosinophils are present throughout the airway wall of asthmatics. The nature of the interaction between human airway smooth muscle cells (ASMC) and eosinophils was investigated in this study. We demonstrated, using light microscopy, that freshly isolated eosinophils from healthy donors rapidly attach to ASMC in vitro. Numbers of attached eosinophils were highest at 2 h, falling to 50% of maximu...
متن کاملgm-csf differentially regulates eosinophil and neutrophil adhesive interactions with vascular endothelium in vivo
allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. granulocyte macrophage colony stimulating factor (gm-csf) is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial...
متن کاملMacrophage-eosinophil interactions in the inflammatory response to Trichinella spiralis.
eosinophils accumulate in vivo, although a tissue reaction to administered antigen has been shown to be a prerequisite for the response. The present experiments aim to understand the significance of the tissue reaction to parasitic larvae in the chain of events leading to eosinophilia. Trichinella spiralis larvae were injected intraperitoneally in rats, and the peritoneal exudate was examined a...
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ژورنال
عنوان ژورنال: Ensho Saisei
سال: 2001
ISSN: 1346-8022,1880-5795
DOI: 10.2492/jsir.21.571